benchexcal - Benchmark, Expand, and Calibrate (BenchExCal) Trial Emulation
Tools
Lightweight tools for evaluating real-world evidence (RWE)
studies that emulate randomized clinical trials (RCTs).
Provides (1) computation of the three pre-specified
RCT-DUPLICATE / ENCORE agreement metrics -- statistical
significance agreement (SA), estimate agreement (EA), and
standardized difference agreement (SD) -- and (2) the
Benchmark, Expand, and Calibrate (BenchExCal) calibration of a
Stage 2 RWE study using the divergence observed in a Stage 1
RCT-RWE pair, plus tipping-point sensitivity analysis and
forest plots. Methods follow Wang et al. JAMA 2023;329:1376 and
Wang et al. CPT 2025;117:1820.